| 发明名称 |
HIGH AFFINITY HUMANIZED ANTI-TAG-72 MONOCLONAL ANTIBODIES |
| 摘要 |
Novel humanized monoclonal antibodies, humanized antibody fragments, and derivatives thereof which specifically bind TAG-72 are provided as well as methods for their manufacture. These humanized antibodies are useful in the treatment of cancers which express TAG-72 as well as for diagnostic purposes, e.g., for in vivo imaging of tumors or cancer cells which express TAG-72.
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| 申请公布号 |
CA2321932(A1) |
申请公布日期 |
1999.09.02 |
| 申请号 |
CA19982321932 |
申请日期 |
1998.02.25 |
| 申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
ARMOUR, KATHRYN;HARRIS, WILLIAM J.;CARR, FRANK J.;TEMPEST, PHILIP R.;ANDERSON, WILLIAM HENRY KERR |
| 分类号 |
A61K38/00;A61K39/395;A61K47/48;A61K51/00;A61P35/00;C07K16/30;C07K16/46;C07K17/00;C12N15/09;C12N15/13;C12Q1/68;G01N33/574;G01N33/577;(IPC1-7):C12N15/13;A61K51/10;C12N15/62;C12N15/85 |
主分类号 |
A61K38/00 |
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