发明名称 |
CARRIER POLYMERS MIGRATING INTO TARGET ORGANS AND DRUG-CONTAINING POLYMERS |
摘要 |
Polymers derived from polymers represented by general Formula (A) (wherein d is from 20 to 500; and Rs, which may be the same or different, represent each H, alkyl or benzyl) by substituting a part or all of the constituting peptide bonds by (1) hydrazino-Glu (Formula B) and saccharide-modified Glu (Formula C), or by (2) hydrazino-Glu (Formula B) and saccharide-modified Glu (Formula C) and drug bonded Glu (Formula D). These polymers, which are carriers optionally bonded to drugs capable of migrating into target organs (cells), are useful as medicines.
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申请公布号 |
WO9943736(A1) |
申请公布日期 |
1999.09.02 |
申请号 |
WO1999JP00872 |
申请日期 |
1999.02.25 |
申请人 |
ONO PHARMACEUTICAL CO., LTD.;HASHIDA, MITSURU;AKAMATSU, KEN |
发明人 |
HASHIDA, MITSURU;AKAMATSU, KEN |
分类号 |
A61K47/48;C08G69/10;C08G69/48;(IPC1-7):C08G69/48;A61K47/42;C07K14/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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