| 摘要 |
<p>Method and composition for treating painful conditions of the body and of the anorectal region. The compositions include a combination of nitroglycerin and sucralfate or a combination of nitroglycerin, lidocaine and sucralfate. The compositions also include a combination of an α-adrenergic blocker and sucralfate, a combination of α-adrenergic blocker and lidocaine, and a combination of an α-adrenergic blocker, lidocaine, and sucralfate. Alternatively, the composition may contain only an α-adrenergic blocker. Additional active ingredients for reduction of anal pain may be added to the composition, particularly capsaicin. The compositions may be included in a petrolatum base along with a water soluble lubricant. These compositions have been found effective in treating painful conditions in the anal region such as anal fissures, inflamed or recently thrombosed hemorrhoids, and chronic anal pain.</p> |
