发明名称 Nucleic acid-containing composition, preparation and use thereof
摘要 PCT No. PCT/FR96/00248 Sec. 371 Date Aug. 15, 1997 Sec. 102(e) Date Aug. 15, 1997 PCT Filed Feb. 15, 1996 PCT Pub. No. WO96/25508 PCT Pub. Date Aug. 22, 1996Pharmaceutical composition useful for transfecting a nucleic acid and characterised in that it contains, in addition to the nucleic acid, at least one transfecting agent and a compound causing the condensation of the nucleic acid, wherein the compound is totally or partly derived from a histone, a nucleoline, a protamine and/or a derivative thereof. The use of the composition for transferring nucleic acids in vitro, ex vivo and/or in vivo is also described.
申请公布号 US5945400(A) 申请公布日期 1999.08.31
申请号 US19970894339 申请日期 1997.08.15
申请人 RHONE-POULENC RORER SA 发明人 SCHERMAN, DANIEL;BYK, GERARDO;SCHWARTZ, BERTRAND
分类号 C12N15/09;A61K9/127;A61K31/785;A61K38/00;A61K39/395;A61K47/34;A61K48/00;C08L83/06;C12N15/87;(IPC1-7):A61K38/10;A61K38/08;C07K9/00;C07K7/00 主分类号 C12N15/09
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