| 摘要 |
PCT No. PCT/EP96/03401 Sec. 371 Date May 1, 1998 Sec. 102(e) Date May 1, 1998 PCT Filed Aug. 2, 1996 PCT Pub. No. WO97/06146 PCT Pub. Date Feb. 20, 1997The present invention relates to a new process for preparing norbenzomorphan, the central intermediate step in the preparation of pharmaceutically useful benzomorphan derivatives of general formula 1 especially (-)-(1R,5S,2''R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzomorphan or [(-)-(2R,6S,2'R)-3-(2-methoxypropyl)-6,11,11-trimethyl-1,2,3,4,5,6 -hexahydro-2,6-methano-benzo[ alpha ]oxacin-9-ol] (BIII 277).
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