Stable intravenously-administrable immune globulin preparation

摘要

Stable, intravenously-administrable immune globulin preparations are stabilized against aggregation and polymerization and rendered isotonic with amino acid(s) and non-ionic detergents, polysorbate and polyethylene glycol. The immunoglobulins are derived from human or animal sources, or from hybridomas. Optional, additional stabilizers include various physiologically-acceptable carbohydrates and salts. Polyvinylpyrrolidone can be used in addition to the amino acid(s). Apart from the immunoglobulin itself, the preparations are otherwise essentially protein free. The preparations are useful in immunotherapy and as diagnostic reagents.