发明名称 |
Process for producing trypsin (trypsinogen) |
摘要 |
Trypsin (trypsinogen) may be produced in a filamentous fungus by transforming a filamentous fungus with a vector comprising a DNA sequence encoding protrypsin or a derivative thereof N-terminally fused to a DNA sequence encoding a signal peptide, culturing the transformed filamentous fungus in a suitable culture medium to produce trypsinogen and recovering trypsinogen and/or trypsin from the medium.
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申请公布号 |
US5945328(A) |
申请公布日期 |
1999.08.31 |
申请号 |
US19970956267 |
申请日期 |
1997.10.22 |
申请人 |
NOVO NORDISK A/S |
发明人 |
WOLDIKE, HELLE FABRICIUS;KJELDSEN, THOMAS BORGLUM |
分类号 |
C12N1/15;C12N9/76;(IPC1-7):C12N1/15;C12N15/55;C12N15/80 |
主分类号 |
C12N1/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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