发明名称 Novel substances kf-1040 and process for producing the same
摘要 A process for producing a substance KF-1040A represented by formula (I), and another substance KF-1040B represented by formula (II), which comprises culturing microorganisms capable of producing the substances KF-1040A and KF-1040B, thus accumulating these KF-1040A and/or KF-1040B in the liquid culture and harvesting the same from the culture. Because of the activities of inhibiting diacyloglycerol transferase and sphingomyelinase, the above substances are useful in preventing and treating arteriosclerosis, obesity, thrombus, inflammation and immune function-related diseases. <CHEM>
申请公布号 AU5880798(A) 申请公布日期 1999.08.30
申请号 AU19980058807 申请日期 1998.02.16
申请人 THE KITASATO INSTITUTE 发明人 SATOSHI OMURA;HIROSHI TOMODA;ROKURO MASUMA
分类号 A61K31/7012;A61K31/7032;C07H;C07H15/10;C12N1/14;C12P7/06;C12P17/06;C12P19/44 主分类号 A61K31/7012
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