| 摘要 |
In accordance with the present invention, there are provided modified forms of pharmacologically active agents (e.g., anti-inflammatory agents) which provide increased/prolonged circulating levels of the active agent, thereby allowing administration of reduced levels of the agent to the recipient. This not only reduces the cost of drug, it also reduces the level to which the recipient is exposed to potentially harmful agents. Invention compounds provide a new class of pharmacologically active agents which cause a much lower incidence of side effects due to the benefits obtained by modifying the pharmacologically active agents as described herein. |
