发明名称 HETEROGENEOUS MOLECULAR LIPID(CHML)OF AFFINITY TO CELL AND MANUFACTURE THEREOF
摘要 A series of cytotropic heterogenous molecular lipids (CHML) and the method of preparation thereof are disclosed in the invention. CHML provided by this invention is in molecular type, it is an activated molecular carrier of functions with orientionally penetrating into membranes or walls of the cells. It possesses the active site for binding anticarcinogenic drugs whichis water soluble, lipid soluble or gas soluble and possesses the activated portion for binding structure of membrane of cancer cells also. CHML can syergetically injure the carcinoma cells and various virus, at the same time it can enhance the immunity of the body. These are ascertained by the animal tests and in vitro tests. CHML in this invention can kill the sarcoma cell S-180 withing 50 min. and the cells of human squamous cell carcinoma of esophagus within 40 min. The rate of DNA and RNA depolymerizations in cancer cells and mortality of cancer cells are attained to 100%. These are evidenced in the vitro test also.
申请公布号 JP2939512(B2) 申请公布日期 1999.08.25
申请号 JP19890296296 申请日期 1989.11.16
申请人 SHIYUU JIYAN 发明人 SHIYUU JIYAN
分类号 A61K9/107;A61K31/015;A61K31/047;A61K31/07;A61K31/19;A61K31/20;A61K31/22;A61K31/355;A61K31/557;A61K31/59;A61P3/02;A61P9/12;A61P31/12;A61P35/00;A61P37/04;A61P43/00 主分类号 A61K9/107
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