PERCUTANEOLIS ABSORPTION TYPE PREPARATION

摘要

PROBLEM TO BE SOLVED: To obtain the subject preparation having excellent skin adhesiveness, initial absorption of tulobuterol and durability of effective concentration in blood, by adding a specific amount or more of tulobuterol in a dissolved state to a paste layer. SOLUTION: This preparation is obtained by laminating a paste layer containing tulobuterol and a tacky agent such as preferably an acrylic tacky agent, a rubber-based tacky agent or the like to a substrate and adding >=5 wt.%, preferably >=10 wt.% of tulobuterol in a dissolved state to the paste layer.