| 摘要 |
PCT No. PCT/IB95/00040 Sec. 371 Date Aug. 28, 1996 Sec. 102(e) Date Aug. 28, 1996 PCT Filed Jan. 19, 1995 PCT Pub. No. WO95/27073 PCT Pub. Date Oct. 12, 1995A new process for recovering high purity natamycin from fermentation broth containing natamycin comprises the steps of adjusting the pH of the broth to above about 10 and adding an amount of a water-miscible solvent, such as isopropanol, sufficient to dissolve the natamycin in the broth, followed by removing insoluble solids from the pH-adjusted broth, followed by lowering the pH of the broth to a level sufficient to precipitate the natamycin, and removing the natamycin from the broth.
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