| 发明名称 |
LH-RH antagonists having improved action |
| 摘要 |
New LH-RH antagonists are disclosed, in particular peptidomimetics and peptides modified in a side chain, their salts with pharmaceutically acceptable acids and a process for preparing these LH-RH antagonists and their salts. The disclosed peptides represent analogues of the luteinising hormone releasing hormone (LH-RH). The disclosed compounds have a high antagonistic power and are free of undesirable side effects, in particular edematogenic effects.
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| 申请公布号 |
US5942493(A) |
申请公布日期 |
1999.08.24 |
| 申请号 |
US19980087274 |
申请日期 |
1998.05.28 |
| 申请人 |
ASTA MEDICA AKTIENGESELLSCHAFT |
发明人 |
KUTSCHER, BERNHARD;BERND, MICHAEL;BECKERS, THOMAS;KLENNER, THOMAS;EMIG, PETER-PAUL;CHARPENTIER, PATRICIA-MARIE |
| 分类号 |
C07D207/26;C07D207/27;C07D209/08;C07D213/61;C07D213/64;C07D213/75;C07D213/80;C07D215/22;C07D231/56;C07D233/26;C07D235/14;C07D239/42;C07D257/04;C07D307/52;C07D471/04;C07D521/00;(IPC1-7):A61K38/00;A61K38/02;C07K5/00;C07K7/00 |
主分类号 |
C07D207/26 |
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