Process for identification of substances modulating ureI dependent mechanisms of Helicobacter pylori metabolism

摘要

The present invention provides a screening process for the identification of anti-helicobactericidal substances modulating ureI dependent mechanisms of gastric Helicobacter metabolism. Gastric Helicobacter cells are treated with a substance to be tested for modulating ureI dependent mechanisms of gastric Helicobacter metabolism and gastric Helicobacter acid resistance or sensitivity to urea is determined.