发明名称 Five-membered, benzo-condensed heterocycles used as antithrombotic agents
摘要 The invention relates to new five-membered, heterocyclic condensed benzoderivatives of the general formula (I), in which Ra to Rc, A, Ar, X and Y have the meanings assigned in claim 1, and their tautomers, stereoisomers, mixtures and salts, especially their physiologically compatible salts with inorganic or organic acids or bases, which have valuable properties. The compounds of the general formula (I) above, in which Rc is a cyano group, present valuable intermediate products for the production of the remaining compounds of the general formula (I), and the compounds of the above general formula (I), in which Rc is one of the following amidino groups, as well as their tautomers and stereoisomers, have valuable pharmacological properties, especially an antithrombotic activity.
申请公布号 AU2720199(A) 申请公布日期 1999.08.23
申请号 AU19990027201 申请日期 1999.01.28
申请人 BOEHRINGER INGELHEIM PHARMA KG 发明人 DR UWE RIES;NORBERT HAUEL;GERHARD MIHM;HENNING PRIEPKE;KLAUS BINDER;JEAN MARIE STASSEN;WOLFGANG WIENEN;RAINER ZIMMERMANN
分类号 C07D277/66;A61K31/403;A61K31/404;A61K31/415;A61K31/4164;A61K31/4184;A61K31/423;A61K31/428;A61K31/4427;A61K31/443;A61K31/4439;A61K31/454;A61K31/4709;A61K31/4725;A61K31/496;A61K31/502;A61K31/5355;A61K31/5377;A61P7/02;A61P9/10;C07D209/14;C07D209/24;C07D235/16;C07D263/56;C07D277/28;C07D277/64;C07D307/81;C07D401/04;C07D401/06;C07D401/08;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/08;C07D403/12;C07D403/14;C07D405/12;C07D405/14;C07D417/12;C07F9/32;C07F9/6506 主分类号 C07D277/66
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