发明名称 |
A PROKARYOTIC CELL COMPRISING TWO COPIES OF A GENE TRANSCRIBED IN DIFFERENT DIRECTIONS |
摘要 |
A prokaryotic cell expressing a gene of interest and comprising at least two copies of said gene on the chromosome. The copies are transcribed in different directions thereby avoiding homologous cross out. The DNA-segment between the two copies does not comprise any information essential for cell growth, e.g. an antibiotic resistance gene.
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申请公布号 |
WO9941358(A1) |
申请公布日期 |
1999.08.19 |
申请号 |
WO1999DK00064 |
申请日期 |
1999.02.10 |
申请人 |
NOVO NORDISK A/S |
发明人 |
JOERGENSEN, STEEN, TROELS |
分类号 |
C12N15/09;C12N1/21;C12N15/74;C12N15/75;C12P21/00;(IPC1-7):C12N1/21 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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