| 发明名称 |
TREATING AND DIAGNOSING MACROPHAGE-MEDIATED DISEASES USING FC RECEPTOR LIGANDS |
| 摘要 |
The invention provides methods and compositions for selectively targeting macrophages in a localized area. The compositions of the invention include an Fc receptor binding agent, and a toxic or a detectable agent. Methods for depleting or inhibiting the activity of macrophages using the compositions of the invention are disclosed. The compositions of the invention can be used therapeutically and diagnostically.
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| 申请公布号 |
CA2321136(A1) |
申请公布日期 |
1999.08.19 |
| 申请号 |
CA19992321136 |
申请日期 |
1999.02.17 |
| 申请人 |
MEDAREX, INC. |
发明人 |
VAN DE WINKEL, JAN G. J. |
| 分类号 |
A61K38/00;A61K39/395;A61K45/06;A61K47/48;A61P11/00;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P31/18;A61P43/00;C07K16/28;C12N5/06;G01N33/50;G01N33/68;(IPC1-7):C07K16/28 |
主分类号 |
A61K38/00 |
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