| 发明名称 |
GENETIC VACCINE VECTOR ENGINEERING |
| 摘要 |
This invention provides methods of obtaining genetic vaccines by use of DNA shuffling. Through use of the claimed methods, vectors can be obtained which exhibit efficacy for use as genetic vaccines. Vectors obtained by using the methods can have, for example, enhanced antigen expression, increased uptake into a cell, increased stability in a cell, ability to tailor an immune response, and the like.
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| 申请公布号 |
CA2320626(A1) |
申请公布日期 |
1999.08.19 |
| 申请号 |
CA19992320626 |
申请日期 |
1999.02.10 |
| 申请人 |
MAXYGEN, INC. |
发明人 |
PUNNONEN, JUHA;WHALEN, ROBERT GERALD;HOWARD, RUSSELL;STEMMER, WILLEM P.C. |
| 分类号 |
C12N15/09;A61K35/76;A61K39/00;A61K45/00;A61K48/00;A61P11/06;A61P29/00;A61P31/00;A61P35/00;A61P37/04;A61P37/06;A61P37/08;C07K14/02;C07K14/16;C07K14/24;C07K14/54;C07K14/705;C12N5/10;C12N15/10;C12Q1/68;C12Q1/70;C40B40/02;G01N33/15;G01N33/50;G01N33/566;(IPC1-7):C12N15/10;C12N15/86 |
主分类号 |
C12N15/09 |
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