发明名称 STEREOSELECTIVE Tc-99m LIGANDS
摘要 <p>The present invention concerns novel ligands, represented by Formulae (I), (II), (I') and (II'), that form complexes with a radioactive metal through a chelate bond. The complexes are useful in radiodiagnostic compositions employed for imaging. In said formulae, X, R?1 and R2, R3 and R4, R5 and R6¿, m and n are defined herein. The compounds of the invention avoid the formation of diastereomers based on incorporating [TcvO]+3N2S2 as a chelating moiety since these compounds form only one isomer when complexed with [?99mTc][TcvO]+¿.</p>
申请公布号 WO1999040882(A2) 申请公布日期 1999.08.19
申请号 US1999002513 申请日期 1999.02.05
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