发明名称 STABLE HYPERFORIN SALTS, METHODS OF MANUFACTURING THEM, AND THEIR USE FOR THE TREATMENT OF ALZHEIMER'S DISEASE
摘要 The invention relates to new hyperforin and adhyperforin salts, methods for producing same and their use. The cation of said salts is either an alkali metal ion or an ammonia ion of a salt-forming nitrogenous base, which saltforming nitrogenous base is preferably a pharmaceutically active ingredient. The salts are used, among other things, for enriching or obtaining in the pure form hyperforin and adhyperforin from St. John's wort extracts and for the stable storage of hyperforin, adhyperforin and their mixtures. The pharmaceutical preparations containing said salts are used in the treatment of Alzheimer's disease. The treatment of Alzheimer's disease is cited as second medical indication for medicines containing hyperforin, adhyperforin or their mixtures.
申请公布号 CA2320091(A1) 申请公布日期 1999.08.19
申请号 CA19992320091 申请日期 1999.02.04
申请人 DR. WILLMAR SCHWABE GMBH & CO. 发明人 CHATTERJEE, SHYAM SUNDER;ERDELMEIER, CLEMENS;KLESSING, KLAUS;MARME, DIETER;SCHACHTELE, CHRISTOPH
分类号 A61P25/28;A61K31/122;C07C45/78;C07C49/653;C07C49/743;C07C211/62;(IPC1-7):C07C50/36;A61K35/78 主分类号 A61P25/28
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