MEDICAL LIPOSOME, AND MINUTE AEROSOL PARTICLE OF MEDICAMENT-CONTAINING LIPOSOME

摘要

PROBLEM TO BE SOLVED: To provide liposome useful for medical use and minute aerosol particle composed of combination of liposome and medicinal substances, and to provide a method for preparing the particle. SOLUTION: This minute aqueous aerosol particle is prepared by atomizing liposome particles having uneven-diameter-liposome membrane and at least one of medicinal substances both in an aqueous medium together with air or oxygen-rich one by an atomizer. The resultant aqueous aerosol particle contains (A) at least one of liposome particles having a uniform and 1μm or less diameter and (B) at least one of lipophilic medicinal substances bound by liposome membrane, and has, for the most part, a diameter of 1-5μm and its aerodynamic diameter around center of mass of 1-3μm.