发明名称 |
PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers |
摘要 |
PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them suitable for encapsulation or solubilization of hydrophobic or water-insoluble materials; and they also form bioerodible matrices for the sustained release of active agents, especially when the POE block(s) contain at least one unit containing an alpha -hydroxy acid.
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申请公布号 |
US5939453(A) |
申请公布日期 |
1999.08.17 |
申请号 |
US19980090648 |
申请日期 |
1998.06.04 |
申请人 |
ADVANCED POLYMER SYSTEMS, INC. |
发明人 |
HELLER, JORGE;NG, STEVEN Y. |
分类号 |
C07D493/10;A61K9/107;A61K9/20;A61K9/51;A61K47/34;C08G63/664;C08G65/00;C08G81/00;C08L71/02;C08L101/16;(IPC1-7):A61K31/335;C07D319/08 |
主分类号 |
C07D493/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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