摘要 |
For the treatment of cancer, inflammation, and other conditions associated with matrix metalloproteinases or that are mediated by TNF alpha or enzymes involved in the shedding of L-selectin, CD23, the TNF receptors, IL-1 receptors, or IL-6 receptors, disclosed are compounds of the general formula B-X-(CH2)m-(CR1R2)n-W-COY. |