发明名称 SPIROCYCLIC INHIBITORS OF METALOPROTEASES
摘要 The invention provides compounds of formula as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metalloproteases. Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.
申请公布号 PL331920(A1) 申请公布日期 1999.08.16
申请号 PL19970331920 申请日期 1997.08.22
申请人 THE PROCTER & GAMBLE CO. 发明人 NATCHUS MICHAEL GEORGE;DE BISWANATH;PIKUL STANISLAW;ALMSTEAD NEIL GREGORY;TAIWO YETUNDE OLABISI;WANG ZHE;BRADLEY RIMMA SANDLER
分类号 C07D487/10;A61K31/40;A61K31/403;A61K31/407;A61K31/435;A61K31/438;A61K31/527;A61P1/02;A61P1/04;A61P3/00;A61P3/04;A61P3/10;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P13/12;A61P15/06;A61P15/08;A61P15/18;A61P17/00;A61P17/02;A61P17/06;A61P17/14;A61P19/02;A61P19/04;A61P21/00;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P31/00;A61P31/04;A61P31/12;A61P31/18;A61P31/22;A61P33/02;A61P33/06;A61P35/00;A61P35/02;A61P37/06;A61P37/08;A61P39/02;A61P41/00;A61P43/00;C07D207/48;C07D209/54;C07D209/96;C07D471/10;C07D491/10;C07D491/113;C07D491/20;C07D493/20;C07D495/10;(IPC1-7):C07D495/10 主分类号 C07D487/10
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