PREVENTIVES AND REMEDIES FOR ISCHEMIC REFLOW DISORDER

摘要

Preventives and remedies for ischemic reflow disorder containing chromanol glycosides represented by general formula (1) as the active ingredient: wherein R<1>, R<2>, R<3> and R<4> are the same or different and each represents hydrogen or lower alkyl; R<5> represents hydrogen, lower alkyl or lower acyl; X represents a monosaccharide or oligosaccharide residue wherein hydroxylic hydrogen therein may be substituted by lower alkyl or lower acyl; n is an integer of 0 to 6; and m is an integer of 1 to 6. These drugs can efficaciously and safely exert their effects on the affected parts even in a small dose to thereby prevent and treat ischemic reflow disorder in the heart, stomach, small intestine, liver, pancreas, kidney, brain, skin, organ transplantation, etc.