Inhibierung von CD95-unabhängiger Apoptose bei AIDS
摘要
The invention relates to a method for inhibiting CD95-independent apoptosis comprising the following steps: (a) blocking the bonding of HIV-1 gp120 on receptors CD4 and/or CXCR4 or of a factor which competes for this bonding, and/or (b) inhibiting the signal path induced by the bonding of (a). The invention also relates to a system for identifying substances which can be utilized for inhibiting CD95-independent apoptosis.
申请公布号
DE19801265(C1)
申请公布日期
1999.08.12
申请号
DE19981001265
申请日期
1998.01.15
申请人
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS, 69120 HEIDELBERG, DE
发明人
KRAMMER, PETER H., 69120 HEIDELBERG, DE;BERNDT, CHRISTINA, 69115 HEIDELBERG, DE