BIBAPCITIDE-BASED PHARMACEUTICAL COMPOSITIONS FOR IMAGING AND TREATING THROMBI

摘要

The invention provides novel precursor reagents used in production of imaging agents derived from apcitide. Imaging agents made using the precursor reagents of the invention are useful for in vivo detection and diagnosis of thrombi. The precursor reagents of the invention may also be used in production of antithrombotic agents derived from apcitide. The presence of the free carboxylate groups affords the precursor reagents greater solubility than bibapcitide in aqueous media.