The invention relates to a method for producing baccatin and/or baccatin derivatives. According to said method, 10-desacetyl baccatin or a derivative thereof is reacted in the presence of an isolated enzyme and an acetyl donor. An acetyl transferase with a molecular weight of between 70 and 72 kD, determined by SDS-PAGE, is used as the enzyme. Said acetyl transferase can be obtained from cell cultures of Taxus chinensis.
申请公布号
WO9940216(A1)
申请公布日期
1999.08.12
申请号
WO1999EP00599
申请日期
1999.01.29
申请人
INDENA S.P.A.;BOMBARDELLI, EZIO;MENHARD, BIRGITTA;ZENK, MEINHART, HANS
发明人
BOMBARDELLI, EZIO;MENHARD, BIRGITTA;ZENK, MEINHART, HANS