摘要 |
<p>A method for determining the presence of an immunoprotective level of an antibody in a vertebrate comprises applying a blood sample from the vertebrate to a chromatographic device and allowing the sample to move through a first and second detection zones on the device. The first detection zone contains an amount of antigen capable of binding to an amount of antibody corresponding to a minimum immunoprotective level of the antibody. The presence of the target antibody in the second detection zone indicates an immunoprotective level of antibody. A class of high sensitivity signal-generating conjugates containing dextran-avidin polymer carrier is provided which is used as internal standard in another assay method of the invention. A method and system for determining the immune status of a vertebrate and for automatically formulating a customized multicomponent vaccine is provided.</p> |