The invention relates to activation of apoptosis by means of interference of Hou-like and/or IFP35-like compounds. Also the invention relates to anti-tumor therapies with compounds, which negatively interfere with Hou-like and/or IFP35-like compounds leading to induction of apoptosis, resulting in the elimination of tumor cells. Also the invention relates to therapies for diseases related to aberrant apoptosis induction, such as auto-immune disease. Also the invention describes the diagnosis of cells, which are susceptible to apoptin- or apoptin-like induced apoptosis.
申请公布号
WO9928460(A3)
申请公布日期
1999.08.12
申请号
WO1998NL00687
申请日期
1998.12.03
申请人
LEADD B.V.;NOTEBORN, MATHIEU, HUBERTUS, MARIA;DANEN-VAN OORSCHOT, ASTRID, ADRIANA, ANNA, MARIA
发明人
NOTEBORN, MATHIEU, HUBERTUS, MARIA;DANEN-VAN OORSCHOT, ASTRID, ADRIANA, ANNA, MARIA