发明名称 THE NIP3 FAMILY OF PROTEINS
摘要 The present invention provides an isolated and purified Nip, Nix and Nox proteins. There is also provided a method for inducing apoptosis in cells by transfecting a cell with a Nip, Nix and Nox proteins. Additionally, there is provided a method for inducing apoptosis in cells by creating antibodies which recognize a specific Nip, Nix and Nox proteins in a muscle or skin of a patient. A method for inducing apoptosis in cells by creating a transgene overexpressing the gene for the Nip, Nix and Nox proteins is also provided. A transgenic animal and progeny thereof is provided having an expression factor consisting essentially of a Nip, Nix and Nox proteins selected from the group consisting essentially of Seq. ID No:1 through 6.
申请公布号 WO9927093(A3) 申请公布日期 1999.08.12
申请号 WO1998IB01959 申请日期 1998.11.24
申请人 UNIVERSITY OF MANITOBA;MANITOBA CANCER TREATMENT & RESEARCH FOUNDATION;GREENBERG, ARNOLD, H. 发明人 GREENBERG, ARNOLD, H.
分类号 A61K48/00;C07K14/47;C12N15/12 主分类号 A61K48/00
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