METHOD OF RECOVERING TRANSLATION ACTIVITY DEPENDENT ON p53 IN CELLS, SINGLE-CHAIN ANTIBODIES AGAINST p53 AND DNA ENCODING THEREOF, THEIR USE AND PREPARATIONS IN WHICH THEY ARE COMPRISED

摘要

The invention concerns single-chain antibodies directed against the p53 protein, capable of being expressed in tumoral cells, capable of restoring a DNA binding in vitro and a transcription activator function in vivo. The invention also concerns nucleic acids coding for these molecules, the vectors containing them and their uses.