发明名称 |
MIRROR-SYMMETRICAL SELECTION AND EVOLUTION OF NUCLEIC ACIDS |
摘要 |
A method is disclosed for identifying and producing L-nucleic acids which interact with a target molecule having a natural configuration, as well as the L-nucleic acids produced by this method. Also disclosed is the use of D-nucleic acids which bind to the optical antipode of the target molecule as a matrix for producing L-nucleic acids with an identical sequence, and pharmaceutical compositions and kits which contain the disclosed L-nucleic acids. |
申请公布号 |
EP0934331(A2) |
申请公布日期 |
1999.08.11 |
申请号 |
EP19970942899 |
申请日期 |
1997.08.29 |
申请人 |
FUERSTE, JENS PETER;BALD, ROLF;ERDMANN, VOLKER A. |
发明人 |
FUERSTE, JENS PETER;BALD, ROLF;ERDMANN, VOLKER A. |
分类号 |
C12N15/09;A01N63/00;A23L27/23;A23L29/00;A61K31/7088;A61P9/12;A61P31/12;A61P35/00;C07H21/00;C12N15/10;C12N15/113;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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