| 发明名称 |
Use of hydrophobic interaction chromatography to purify polyethylene glycols |
| 摘要 |
The present invention relates to a process for purifying polyethylene glycols (PEGs) which utilizes hydrophobic interaction chromatography (HIC) to separate the PEGs based on their size and on their end-group functionality. The purified PEGs can be used to modify biologically active molecules and improve overall production of such molecules.
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| 申请公布号 |
US5935564(A) |
申请公布日期 |
1999.08.10 |
| 申请号 |
US19970936478 |
申请日期 |
1997.09.18 |
| 申请人 |
AMGEN INC. |
发明人 |
SEELY, JAMES ERVIN |
| 分类号 |
A61K38/00;A61K31/00;A61K45/00;A61K47/48;A61P29/00;A61P31/00;A61P31/04;C07K14/48;C07K17/08;(IPC1-7):A61K31/795;B01D15/08;C08G65/00 |
主分类号 |
A61K38/00 |
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