Process for the preparation of 1,2-dioxetane compounds and novel sulfur-substituted 1,2-dioxetane compounds as intermediates

摘要

PCT No. PCT/US96/09248 Sec. 371 Date Dec. 22, 1997 Sec. 102(e) Date Dec. 22, 1997 PCT Filed Jun. 19, 1996 PCT Pub. No. WO97/00869 PCT Pub. Date Jan. 9, 1997A process for producing a stable triggerable dioxetane comprising; (a) reacting a vinyl sulfide compound containing a sulfur-substituent SR4, wherein R4 is an organic group containing 1 to 20 carbon atoms and optionally heteroatoms, with oxygen and light in the presence of a photosensitizer to form an intermediate sulfur-substituted dioxetane compound; and (b) reacting the sulfur-substituted dioxetane compound with an electrophilic compound E-Y and a hydroxylic compound R5OH selected from the group consisting of alcohols, phenols and carboxylic acids or their salts and containing an OR5 group to replace the SR4 group of the dioxetane with the OR5 group.