发明名称 |
Monoclonal antibody that detects apoptotic antigen |
摘要 |
A monoclonal antibody which specifically binds to an antigen on the membrane of mitochondria in apoptotic cells. The antigen is a 38 kD protein that is detectable in cells undergoing apoptosis and undetectable in normal cells. This selectivity of the monoclonal antibody provides a method of distinguishing between normal and apoptotic cells in a sample of human hemopoietic cell populations. A method for detecting and measuring cells undergoing apoptosis is also provided.
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申请公布号 |
US5935801(A) |
申请公布日期 |
1999.08.10 |
申请号 |
US19960623876 |
申请日期 |
1996.03.29 |
申请人 |
DANA-FARBER CANCER INSTITUTE |
发明人 |
SCHLOSSMAN, STUART FRANKLIN;ZHANG, CHONGHUI |
分类号 |
C12N15/02;C07K16/18;C12N5/10;C12N5/20;C12P21/08;G01N33/53;G01N33/577;(IPC1-7):G01N33/53 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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