发明名称 Methods to identify immunomodulators using cognate interaction of PKC-theta
摘要 Modulators of the immune system can be identified by determining the ability of candidate substances to affect the interaction of PKC-theta or a fragment thereof with its cognate. The interaction can be measured using binding of the cognate as an index, or can be measured using a physiological response.
申请公布号 US5935803(A) 申请公布日期 1999.08.10
申请号 US19960665647 申请日期 1996.06.18
申请人 TERRAPIN TECHNOLOGIES, INC. 发明人 VASQUEZ, NICKI J.;RON, DORIT;VORONOVA, ANNA F.;NAPOLITANO, EUGENE W.
分类号 G01N33/566;A61K31/00;A61K38/00;A61K48/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;C07K5/117;C07K14/00;C07K14/40;C07K14/47;C07K14/705;C12N9/12;C12N15/09;C12P21/02;G01N33/15;G01N33/50;G01N33/68;(IPC1-7):C12Q1/02;C12Q1/48;C12Q1/68 主分类号 G01N33/566
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