Piperazinones, their production and use

摘要

PCT No. PCT/JP96/01139 Sec. 371 Date Jul. 10, 1996 Sec. 102(e) Date Jul. 10, 1996 PCT Filed Apr. 25, 1996 PCT Pub. No. WO96/33982 PCT Pub. Date Oct. 31, 1996The present invention provides compounds and medicines effective for prophylaxis and therapy of various diseases by controlling or inhibiting cell-adhesion. Especially, the compounds of this invention perform platelet aggregation action without remarkable elongation of hemorrhagic period and can be used as a safe and long-acting antithrombotic drug as compared with known substances showing the same activity. Compounds of this invention are piperazinones of the formula