摘要 |
<p>Disclosed are compounds of the general formula (I): wherein R1 is a hydrogen atom or alkyl residue containing 1 - 6 carbon atoms; R2 is a hydrogen atom, an alkyl, aryl, aralkyl, or alkylaryl group containing 1-10 carbon atoms, an acyl residue containing 1-10 carbon atoms, or a residue -CONHR4 or -COOR4; R3 is a hydrogen atom, an alkyl, aryl, aralkyl, or alkylaryl group containing 1 - 10 carbon atoms, a residue -(CH2)n-CH2X; Z is a hydrogen atom, an alkyl, aryl, aralkyl, or alkylaryl residue containing 1 - 10 carbon atoms, or an acyl residue containing 1 - 10 carbon atoms, a residue -CONHR4 or -COOR4, or an alkaline or alkaline-earth metal atom; further substituents as defined in the Claims; and pharmaceutically acceptable salts thereof, with the exception of compounds wherein R1 is -CH3, R2 is -CH3, R3 is -CH2-O-CH3 and Z is -CO-CH3, -CO- O-C2H5, -CO-NH-phenyl, -CO-NH-C2H5, -CO-C2H5, or -CO- phenyl; a method of their preparation, pharmaceutical compositions containing these compounds.</p> |