发明名称 USING POLYAMIDE NUCLEIC ACID OLIGOMERS TO ENGENDER A BIOLOGICAL RESPONSE
摘要 The invention provides methods of treating living cells with PNA oligomers such that the oligomers cross a biological barrier and engender a biological response. The invention provides methods for screening potential PNA oligomers for the ability to engender a sequence specific biological response. The invention also provides methods of identifying the function of polypeptides and of determining the relative turnover rate of functional polypeptides.
申请公布号 WO9920643(A9) 申请公布日期 1999.08.05
申请号 WO1998US21888 申请日期 1998.10.16
申请人 MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 发明人 RICHELSON, ELLIOTT;TYLER, BETH, MARIE;MCCORMICK, DANIEL, J.;CUSACK, BERNADETTE, MARIE;HOSHALL, CLARK, V.;DOUGLAS, CHRISTOPHER, LEE;JANSEN, KAREN
分类号 C12N15/09;A61K31/711;A61K38/00;A61K48/00;A61P25/04;A61P25/24;A61P25/28;A61P37/02;A61P43/00;C07K14/00;C12N5/10;C12N15/113;C12Q1/68;(IPC1-7):C07H21/04 主分类号 C12N15/09
代理机构 代理人
主权项
地址