| 摘要 |
<p>The present invention provides a method for treating or preventing a T cell associated disorder in a subject comprising administering to the subject a peptide ligand for the T cell receptor which induces apoptosis of T cells without release of T cell-derived, non-death inducing cytokines by T cells which recognize the peptide ligand. Also provided is a method for enhancing immune tolerance in a transplant recipient comprising administering to the recipient a peptide ligand for the T cell receptor which induces apoptosis of T cells without release of T cell-derived, non-death inducing cytokines by T cells which recognize the peptide ligand. Further provided is a method for inducing apoptosis of T cells without release of T cell-derived, non-death inducing cytokines, comprising contacting the T cells with a peptide ligand for the T cell receptor which induces apoptosis of T cells without release of T cell-derived, non-death inducing cytokines and a method for improving transplantation of bone marrow cells, comprising inducing apoptosis of T cells without release of T cell-derived, non-death inducing cytokines, comprising contacting the T cells with a peptide ligand for the T cell receptor which induces apoptosis of T cells without release of T cell-derived, non-death inducing cytokines.</p> |
