发明名称 PRODUCTION OF 1,3-DIOXOLAN-4-ONE COMPOUND
摘要 PROBLEM TO BE SOLVED: To obtain the subject compound in a high yield by subjecting anα-hydroxycarboxylic acid compound and an arylthioketone compound to a desulfurizing condensation reaction in the presence of a desulfurizing agent and a base. SOLUTION: This method for producing a 1,3-dioxolan-4-one compound of formula III (for example, a compound of formula IV) comprises subjecting (A) anα-hydroxycarboxylic acid compound of formula I [R<1> and R<2> are each H, a (substituted) alkyl or the like] and (B) (i) an arylthioketone compound of formula II (Ar<1> and Ar<2> are each an aryl) to a desulfurizing condensation reaction in the presence of (ii) a desulfurizing agent (for example, Ag) and (iii) a base (for example, a hydroxycarboxylic acid alkali metal salt). The component Bii is preferably used in an amount of at least 1 equivalent per equivalent of the component Bi, and the component Biii is preferably used in an amount of at least 2 equivalents per equivalent of the component A.
申请公布号 JPH11209367(A) 申请公布日期 1999.08.03
申请号 JP19980010334 申请日期 1998.01.22
申请人 AGENCY OF IND SCIENCE & TECHNOL 发明人 SHIBUYA ISAO;GAMA YASUO;SHIMIZU MASAO
分类号 C07D317/34;C07D317/72;C07D493/10;C07D495/10;(IPC1-7):C07D317/34 主分类号 C07D317/34
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