| 发明名称 |
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| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject medicine, comprising a glutamate decarboxylase protein or peptide and effective in treating or preventing insulin-dependent diabetes mellitus. SOLUTION: This medicine comprises a glutamate decarboxylase protein or peptide and preferably further an immunological activating fragment. The fragment contains an amino acid sequence Pro-Glu-Val-Lys. For example, the protein has the homology with a pancreatic 64 K protein in sequence and the 64 K protein has immunological reactivities with the glutamate decarboxylase enzyme. An islet isolated from the human pancreas is preferably used as a material. |
| 申请公布号 |
JP2928176(B2) |
申请公布日期 |
1999.08.03 |
| 申请号 |
JP19960297038 |
申请日期 |
1996.10.21 |
| 申请人 |
YUNIBAASHITEI OBU FURORIDA ZA |
发明人 |
MAAKU EI ATOKINSON;NOERU KEI MAKURAREN;UIRIAMU KASUTAAN |
| 分类号 |
G01N33/53;A61K31/00;A61K38/46;A61K39/00;A61P3/00;A61P3/08;A61P3/10;C12N15/09;G01N33/564 |
主分类号 |
G01N33/53 |
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代理人 |
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| 地址 |
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