| 摘要 |
This invention relates to a group of 2-substituted-1-benzoyl-1,2-dihydroquinolines useful for increasing HDL-C concentration in the blood of a mammal according to formula (I), wherein: R<1> is a carboxamide [-C(O)NH2] or carboxamidoxime [-C(=NOH)NH2]; R<2> is phenyl optionally substituted with one to three groups selected from halogen, alkyl of 1-6 carbon atoms, or perfluoroalkoxy of 1-6 carbon atoms; and R<3> and R<4> are hydrogen, halogen, C1-C6 alkyl or trifluoromethyl and to therapeutic compositions for treating atherosclerotic conditions such as dyslipoproteinamias and coronary heart disease. |
