发明名称 |
Human suppressor trna oligonucleotides and methods of use for same |
摘要 |
Novel synthetic suppressor tRNA have been provided which provide read-through of internal nonsense mutations, or which can site-specifically alter translation of transcribed sequences. Uses of the same are also provided in genetic engineering protocols including gene therapy treatment of diseases such as Xeroderma pigmentosum. |
申请公布号 |
AU2225199(A) |
申请公布日期 |
1999.08.02 |
申请号 |
AU19990022251 |
申请日期 |
1999.01.13 |
申请人 |
HUMAN GENE THERAPY RESEARCH INSTITUTE |
发明人 |
REKHA G. PANCHAL;CHARLES J. LINK JR. |
分类号 |
C12N15/09;A61K31/7105;A61K48/00;A61P17/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/22;C12N15/11;H04B10/24 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|