A polypeptide that functions as an IL-18 receptor is disclosed. The receptor is multimeric and includes at least one AcPL polypeptide, or fragment thereof, and at least one IL-1Rrpl polypeptide, or fraction thereof. The receptor binds IL-18 and finds use in inhibiting biological activities mediated by IL-18.
申请公布号
WO9937772(A1)
申请公布日期
1999.07.29
申请号
WO1999US01419
申请日期
1999.01.22
申请人
IMMUNEX CORPORATION;SIMS, JOHN, E.;BORN, TERESA, L.
