发明名称 |
ASYMMETRIC CYANINE DYE QUENCHERS |
摘要 |
The invention provides an asymmetric cyanine dye compound having structure (1) including substituted forms thereof, wherein, at least one of R1 and R2 is linking group, X is O, S, or Se, and n ranges from 0 to 2. The invention further provides reporter-quencher dye pairs comprising the asymmetric cyanine dyes, dye-labeled polynucleotides incorporating the asymmetric cyanine dyes, and hybridization detection methods utilizing the dye-labeled polynucleotides. |
申请公布号 |
WO9937717(A1) |
申请公布日期 |
1999.07.29 |
申请号 |
WO1999US01163 |
申请日期 |
1999.01.19 |
申请人 |
THE PERKIN-ELMER CORPORATION |
发明人 |
LEE, LINDA, G.;GRAHAM, RONALD, J.;MULLAH, KHAIRUZZAMAN, B.;HAXO, FRANCIS, T. |
分类号 |
G01N33/58;C07D413/06;C07D417/06;C07D421/06;C07D513/04;C07H19/04;C07H21/00;C09B23/00;C09B23/02;C12N15/09;C12Q1/68;G01N21/78 |
主分类号 |
G01N33/58 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|