发明名称 |
ASYMMETRIC CYANINE DYE QUENCHERS |
摘要 |
The invention provides an asymmetric cyanine dye compound having structure (1) including substituted forms thereof, wherein, at least one of R1 and R2 is linking group, X is O, S, or Se, and n ranges from 0 to 2. The invention further provides reporter-quencher dye pairs comprising the asymmetric cyanine dyes, dye-labeled polynucleotides incorporating the asymmetric cyanine dyes, and hybridization detection methods utilizing the dye-labeled polynucleotides.
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申请公布号 |
CA2318160(A1) |
申请公布日期 |
1999.07.29 |
申请号 |
CA19992318160 |
申请日期 |
1999.01.19 |
申请人 |
THE PERKIN-ELMER CORPORATION |
发明人 |
HAXO, FRANCIS T.;LEE, LINDA G.;GRAHAM, RONALD J.;MULLAH, KHAIRUZZAMAN B. |
分类号 |
G01N33/58;C07D413/06;C07D417/06;C07D421/06;C07D513/04;C07H19/04;C07H21/00;C09B23/00;C09B23/02;C12N15/09;C12Q1/68;G01N21/78;(IPC1-7):C09B23/02 |
主分类号 |
G01N33/58 |
代理机构 |
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主权项 |
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地址 |
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