| 摘要 |
<p>A class of substituted 1,2,4-triazolo[4,3-b]pyridazine derivatives of formula (I), wherein Z represents cyclobutyl or pyrrolidin-1-yl, are selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.</p> |
