发明名称 TERPENOID LACTONE COMPOUNDS AND THEIR PRODUCTION PROCESS
摘要 This invention provides terpenoid lactone compounds, and processes for producing the terpenoid lactone compounds, which comprise cultivating Oidiodedron griseum FERM BP-5778 and then isolating the terpenoid lactone compounds from the fermentation broth. The present invention also provides a pharmaceutical composition comprising the terpenoid lactone compound, which is useful in the treatment of IL-1 and TNF mediated diseases or the like.
申请公布号 CA2260413(A1) 申请公布日期 1999.07.29
申请号 CA19992260413 申请日期 1999.01.27
申请人 PFIZER INC. 发明人 NISHIDA, HIROYUKI;YOSHIKAWA, NOBUJI;KOJIMA, NAKAO;IKUNAKA, MASAYA;ICHIKAWA, KATSUOMI
分类号 C12P17/06;A61K31/00;A61K31/365;A61K31/366;A61K31/47;A61K31/4738;A61K31/4741;A61P1/00;A61P9/00;A61P9/10;A61P11/00;A61P29/00;A61P43/00;C07D307/92;C07D311/92;C07D491/06;C07D491/16;C07D491/20;C07D493/06;C07D493/20;C12P17/12;C12R1/645;(IPC1-7):C12N1/14;C12P17/04;C07D493/16;C12P17/18 主分类号 C12P17/06
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